Glossary

What is cortisol?

Cortisol is a hormone made by your adrenal glands, often called the stress hormone. It helps your body respond to stress, and it also helps control blood sugar, blood pressure and inflammation.

Written by Poshan Labs. Sources are named on the page. Last updated 26 October 2026.

Cortisol on your report

Cortisol is usually tested in blood, often in the morning and again around 4 pm, or in urine or saliva.

Because it changes through the day:

  • the time of the sample matters
  • labs print their own ranges for different times

Cortisol: a hormone made by your adrenal glands, often called the stress hormone.

What cortisol tells your doctor

Cortisol follows a daily rhythm: it is highest in the morning and much lower by late afternoon.

Stress and exercise push it up for a while, which is normal. Problems come when it stays too high or too low for a long time.

  • Too much, as in a condition called Cushing's syndrome, can cause weight gain, a rounder face, easy bruising and muscle weakness.
  • Too little can bring tiredness, weight loss and weakness.

These can also raise it:

  • anxiety and depression
  • heavy drinking
  • poorly controlled diabetes
  • obesity

What moves your cortisol

Everyday habits shape how your stress system runs. These all help:

  • a fixed sleep and wake time
  • regular meals instead of long gaps followed by big ones
  • movement you enjoy, like brisk walking or yoga

Simple slow breathing or a short quiet break in a busy day can ease stress.

Long-term steroid medicines are the most common cause of abnormal cortisol, so never stop one suddenly on your own; talk to your doctor first.

The first call is free

Tell Puja what's going on and she will tell you honestly whether she can help.

A question about Cortisol?

Send Puja a message. On a free call she looks at your reports and your plate with you, and says what to change.