Glossary

What is DHEA-S?

DHEA-S (dehydroepiandrosterone sulphate) is a hormone made mostly by your adrenal glands, two small glands that sit on top of your kidneys. Your body uses it as a building block to make other hormones, including testosterone and oestrogen.

Written by Poshan Labs. Sources are named on the page. Last updated 26 October 2026.

DHEA-S on your report

It appears as DHEA-S or DHEA sulphate on a hormone panel, often next to testosterone.

Normal ranges depend heavily on:

  • your age
  • your sex

Each lab prints its own range, so read your value against the range on your report.

DHEA-S: a hormone made mostly by your adrenal glands, two small glands that sit on top of your kidneys.

What DHEA-S tells your doctor

Doctors often check DHEA-S when a woman has signs of too many male-type hormones.

These signs include:

  • extra facial or body hair
  • acne
  • irregular periods
  • hair thinning at the top of the head

What a result can mean:

  • A high level can be seen in PCOS.
  • The test also helps your doctor rule out less common adrenal causes, since DHEA-S comes mainly from the adrenal glands rather than the ovaries.
  • Levels peak in early adulthood and drift down with age, so a lower number in your fifties is usually expected.

What helps when DHEA-S runs high

Food doesn't change DHEA-S directly, but the habits that help PCOS overall are worth building.

  • Regular meals with protein and fibre
  • Fewer refined carbs and sweets
  • Daily movement
  • A fixed sleep time

Looking after stress and sleep supports your whole hormone system.

DHEA pills are sold over the counter and online, but don't start them on your own; talk to your doctor first, because they can change your other hormone levels.

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